Outbreak of Invasive Wound Mucormycosis in a Burn Unit Due to Multiple Strains of Mucor circinelloides f. circinelloides Resolved by Whole-Genome Sequencing
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منابع مشابه
Stress Responses of Genetically Modified Mucor Circinelloides Strains
The stress-related responses of Mucor circinelloides transformants altered in carotenoid production have been investigated. In zygomycetous fungi β-carotene is the predominant carotenoid, however, in transformants containing the crtW and crtZ astaxanthin biosynthesis genes from Agrobacterium aurantiacum new carotenoid compounds are present. Mucor strains with altered carotenoid content were tre...
متن کاملSporangiospore Size Dimorphism Is Linked to Virulence of Mucor circinelloides
Mucor circinelloides is a zygomycete fungus and an emerging opportunistic pathogen in immunocompromised patients, especially transplant recipients and in some cases otherwise healthy individuals. We have discovered a novel example of size dimorphism linked to virulence. M. circinelloides is a heterothallic fungus: (+) sex allele encodes SexP and (-) sex allele SexM, both of which are HMG domain...
متن کاملFungemia and cutaneous zygomycosis due to Mucor circinelloides in an intensive care unit patient: case report and review of literature.
Mucor spp. are rarely pathogenic in healthy adults, but can cause fatal infections in patients with immuosuppression and diabetes mellitus. Documented mucor fungemia is a very rare condition in the literature. We described a fungemia and cutaneous mucormycosis case due to Mucor circinelloides in an 83-year-old woman with diabetes mellitus who developed acute left frontoparietal infarctus while ...
متن کاملAnalysis of a Food-Borne Fungal Pathogen Outbreak: Virulence and Genome of a Mucor circinelloides Isolate from Yogurt
Food-borne pathogens are ongoing problems, and new pathogens are emerging. The impact of fungi, however, is largely underestimated. Recently, commercial yogurts contaminated with Mucor circinelloides were sold, and >200 consumers became ill with nausea, vomiting, and diarrhea. Mucoralean fungi cause the fatal fungal infection mucormycosis, whose incidence has been continuously increasing. In th...
متن کاملexpression of a bacterial β-carotene hydroxylase in canthaxanthin producing mutant Mucor circinelloides strains
Xanthophylls, primarily hydroxyland keto-derivatives of β-carotene (such as zeaxanthin, β-cryptoxanthin, canthaxanthin, echinenone and astaxanthin) have powerful antioxidant activity. Due to several positive effects on human and animal health, industrial application of xanthophylls shows an increasing tendency. In our previous study, carotenoid biosynthesis of the β-carotene producing zygomycet...
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ژورنال
عنوان ژورنال: mBio
سال: 2018
ISSN: 2161-2129,2150-7511
DOI: 10.1128/mbio.00573-18